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In- and ex-vivo molecular imaging of apoptosis to assess sensitivity of non-small cell lung cancer to EGFR inhibitors using probe-based confocal laser endomicroscopy

BACKGROUND: Prediction of treatment outcome of non-small cell lung cancer (NSCLC) with EGFR inhibitors on the basis of the genetic analysis of the tumor can be incorrect in case of rare or complex mutations, bypass molecular activation pathways, or pharmacodynamic variations. The aim of this study w...

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Detalles Bibliográficos
Autores principales: Guisier, Florian, Bohn, Pierre, Patout, Maxime, Piton, Nicolas, Farah, Insaf, Vera, Pierre, Thiberville, Luc, Salaün, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495425/
https://www.ncbi.nlm.nih.gov/pubmed/28671975
http://dx.doi.org/10.1371/journal.pone.0180576