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In- and ex-vivo molecular imaging of apoptosis to assess sensitivity of non-small cell lung cancer to EGFR inhibitors using probe-based confocal laser endomicroscopy
BACKGROUND: Prediction of treatment outcome of non-small cell lung cancer (NSCLC) with EGFR inhibitors on the basis of the genetic analysis of the tumor can be incorrect in case of rare or complex mutations, bypass molecular activation pathways, or pharmacodynamic variations. The aim of this study w...
Autores principales: | Guisier, Florian, Bohn, Pierre, Patout, Maxime, Piton, Nicolas, Farah, Insaf, Vera, Pierre, Thiberville, Luc, Salaün, Mathieu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495425/ https://www.ncbi.nlm.nih.gov/pubmed/28671975 http://dx.doi.org/10.1371/journal.pone.0180576 |
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