Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rats

Activation of the angiotensin II type 2 receptor (AT2R) by administration of Compound 21 (C21), a selective AT2R agonist, induces neuroprotection in models of ischemic stroke in young adult animals. The mechanisms of this neuroprotective action are varied, and may include direct and indirect effects...

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Detalles Bibliográficos
Autores principales: Bennion, Douglas M., Isenberg, Jacob D., Harmel, Allison T., DeMars, Kelly, Dang, Alex N., Jones, Chad H., Pignataro, Megan E., Graham, Justin T., Steckelings, U. Muscha, Alexander, Jon C., Febo, Marcelo, Krause, Eric G., de Kloet, Annette D., Candelario-Jalil, Eduardo, Sumners, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495490/
https://www.ncbi.nlm.nih.gov/pubmed/28671997
http://dx.doi.org/10.1371/journal.pone.0180738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495490/
https://www.ncbi.nlm.nih.gov/pubmed/28671997
http://dx.doi.org/10.1371/journal.pone.0180738

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