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Structural and dynamical insight into thermally induced functional inactivation of firefly luciferase

Luciferase is the key component of light production in bioluminescence process. Extensive and advantageous application of this enzyme in biotechnology is restricted due to its low thermal stability. Here we report the effect of heating up above T(m) on the structure and dynamical properties of lucif...

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Detalles Bibliográficos
Autores principales: Jazayeri, Fatemeh S., Amininasab, Mehriar, Hosseinkhani, Saman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495494/
https://www.ncbi.nlm.nih.gov/pubmed/28672033
http://dx.doi.org/10.1371/journal.pone.0180667