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Novel interplay between JNK and Egfr signaling in Drosophila dorsal closure

Dorsal closure (DC) is a developmental process in which two contralateral epithelial sheets migrate to seal a large hole in the dorsal ectoderm of the Drosophila embryo. Two signaling pathways act sequentially to orchestrate this dynamic morphogenetic process. First, c-Jun N-terminal kinase (JNK) si...

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Detalles Bibliográficos
Autores principales: Kushnir, Tatyana, Mezuman, Sharon, Bar-Cohen, Shaked, Lange, Rotem, Paroush, Ze'ev, Helman, Aharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495517/
https://www.ncbi.nlm.nih.gov/pubmed/28628612
http://dx.doi.org/10.1371/journal.pgen.1006860