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The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
A systematic study of the thermal and conformational properties of chemically modified G-quadruplexes of different molecularities is reported. The effect of backbone charge and atom size, thymine/uracyl substitution as well as the effect of modification at the ribose 2′-position was analyzed by UV s...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549566/ https://www.ncbi.nlm.nih.gov/pubmed/15731338 http://dx.doi.org/10.1093/nar/gki257 |