Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase β and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity

We examined interactions between base excision repair (BER) DNA intermediates and purified human BER enzymes, DNA polymerase β (pol β), apurinic/apyrimidinic endonuclease (APE1) and poly(ADP-ribose) polymerase-1 (PARP-1). Studies under steady-state conditions with purified BER enzymes and BER substr...

Descripción completa

Detalles Bibliográficos
Autores principales: Sukhanova, Maria V., Khodyreva, Svetlana N., Lebedeva, Natalia A., Prasad, Rajendra, Wilson, Samuel H., Lavrik, Olga I.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549570/
https://www.ncbi.nlm.nih.gov/pubmed/15731342
http://dx.doi.org/10.1093/nar/gki266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549570/
https://www.ncbi.nlm.nih.gov/pubmed/15731342
http://dx.doi.org/10.1093/nar/gki266

Ejemplares similares