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Pancreatic cancer: Circulating Tumor Cells and Primary Tumors show Heterogeneous KRAS Mutations

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease. Circulating tumor cells (CTC) in the blood are hypothesized as the means of systemic tumor spread. Blood obtained from healthy donors and patients with PDAC was therefore subject to size-based CTC-isolation. We additionally compared K...

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Detalles Bibliográficos
Autores principales: Kulemann, Birte, Rösch, Stephanie, Seifert, Sindy, Timme, Sylvia, Bronsert, Peter, Seifert, Gabriel, Martini, Verena, Kuvendjiska, Jasmina, Glatz, Torben, Hussung, Saskia, Fritsch, Ralph, Becker, Heiko, Pitman, Martha B., Hoeppner, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495768/
https://www.ncbi.nlm.nih.gov/pubmed/28674438
http://dx.doi.org/10.1038/s41598-017-04601-z