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PAX2 is dispensable for in vitro nephron formation from human induced pluripotent stem cells

The kidney is formed by reciprocal interactions between the nephron progenitor and the ureteric bud, the former of which gives rise to the epithelia of nephrons consisting of glomeruli and renal tubules. The transcription factor PAX2 is essential for this mesenchymal-to-epithelial transition of neph...

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Detalles Bibliográficos
Autores principales: Kaku, Yusuke, Taguchi, Atsuhiro, Tanigawa, Shunsuke, Haque, Fahim, Sakuma, Tetsushi, Yamamoto, Takashi, Nishinakamura, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495778/
https://www.ncbi.nlm.nih.gov/pubmed/28674456
http://dx.doi.org/10.1038/s41598-017-04813-3