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PAX2 is dispensable for in vitro nephron formation from human induced pluripotent stem cells
The kidney is formed by reciprocal interactions between the nephron progenitor and the ureteric bud, the former of which gives rise to the epithelia of nephrons consisting of glomeruli and renal tubules. The transcription factor PAX2 is essential for this mesenchymal-to-epithelial transition of neph...
Autores principales: | Kaku, Yusuke, Taguchi, Atsuhiro, Tanigawa, Shunsuke, Haque, Fahim, Sakuma, Tetsushi, Yamamoto, Takashi, Nishinakamura, Ryuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495778/ https://www.ncbi.nlm.nih.gov/pubmed/28674456 http://dx.doi.org/10.1038/s41598-017-04813-3 |
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