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Insulated transcriptional elements enable precise design of genetic circuits

Rational engineering of biological systems is often complicated by the complex but unwanted interactions between cellular components at multiple levels. Here we address this issue at the level of prokaryotic transcription by insulating minimal promoters and operators to prevent their interaction and...

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Detalles Bibliográficos
Autores principales: Zong, Yeqing, Zhang, Haoqian M., Lyu, Cheng, Ji, Xiangyu, Hou, Junran, Guo, Xian, Ouyang, Qi, Lou, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495784/
https://www.ncbi.nlm.nih.gov/pubmed/28674389
http://dx.doi.org/10.1038/s41467-017-00063-z