Cargando…
Insulated transcriptional elements enable precise design of genetic circuits
Rational engineering of biological systems is often complicated by the complex but unwanted interactions between cellular components at multiple levels. Here we address this issue at the level of prokaryotic transcription by insulating minimal promoters and operators to prevent their interaction and...
Autores principales: | Zong, Yeqing, Zhang, Haoqian M., Lyu, Cheng, Ji, Xiangyu, Hou, Junran, Guo, Xian, Ouyang, Qi, Lou, Chunbo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495784/ https://www.ncbi.nlm.nih.gov/pubmed/28674389 http://dx.doi.org/10.1038/s41467-017-00063-z |
Ejemplares similares
-
Precise programming of multigene expression stoichiometry in mammalian cells by a modular and programmable transcriptional system
por: Qin, Chenrui, et al.
Publicado: (2023) -
Novel switchable ECF sigma factor transcription system for improving thaxtomin A production in Streptomyces
por: Zhao, Xuejin, et al.
Publicado: (2022) -
Precision design of stable genetic circuits carried in highly‐insulated E. coli genomic landing pads
por: Park, Yongjin, et al.
Publicado: (2020) -
Multiplexed Promoter Engineering for Improving Thaxtomin A Production in Heterologous Streptomyces Hosts
por: Zhao, Xuejin, et al.
Publicado: (2022) -
CRISPR-Based Genetic Switches and Other Complex Circuits: Research and Application
por: Du, Pei, et al.
Publicado: (2021)