Quantitative Protein Topography Measurements by High Resolution Hydroxyl Radical Protein Footprinting Enable Accurate Molecular Model Selection

We report an integrated workflow that allows mass spectrometry-based high-resolution hydroxyl radical protein footprinting (HR-HRPF) measurements to accurately measure the absolute average solvent accessible surface area (<SASA>) of amino acid side chains. This approach is based on application...

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Detalles Bibliográficos
Autores principales: Xie, Boer, Sood, Amika, Woods, Robert J., Sharp, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495787/
https://www.ncbi.nlm.nih.gov/pubmed/28674401
http://dx.doi.org/10.1038/s41598-017-04689-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495787/
https://www.ncbi.nlm.nih.gov/pubmed/28674401
http://dx.doi.org/10.1038/s41598-017-04689-3

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