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Genetic association analysis of the RTK/ERK pathway with aggressive prostate cancer highlights the potential role of CCND2 in disease progression

The RTK/ERK signaling pathway has been implicated in prostate cancer progression. However, the genetic relevance of this pathway to aggressive prostate cancer at the SNP level remains undefined. Here we performed a SNP and gene-based association analysis of the RTK/ERK pathway with aggressive prosta...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Zhang, Qin, Wang, Qiuyan, Li, Jie, Sipeky, Csilla, Xia, Jihan, Gao, Ping, Hu, Yanling, Zhang, Haiying, Yang, Xiaobo, Chen, Haitao, Jiang, Yonghua, Yang, Yuehong, Yao, Ziting, Chen, Yinchun, Gao, Yong, Tan, Aihua, Liao, Ming, Schleutker, Johanna, Xu, Jianfeng, Sun, Yinghao, Wei, Gong-Hong, Mo, Zengnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495790/
https://www.ncbi.nlm.nih.gov/pubmed/28674394
http://dx.doi.org/10.1038/s41598-017-04731-4