Cargando…

Dexamethasone induced inhibition of Dectin-1 activation of antigen presenting cells is mediated via STAT-3 and NF-κB signaling pathways

Treatment of patients with glucocorticoids can result in an increased risk of infection with pathogens such as fungi. Dectin-1 is a member of the C-type lectin receptor superfamily and was shown to be one of the major receptors for fungal beta-glucans. Activation of Dectin-1 increases the production...

Descripción completa

Detalles Bibliográficos
Autores principales: Kotthoff, Philipp, Heine, Annkristin, Held, Stefanie Andrea Erika, Brossart, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495798/
https://www.ncbi.nlm.nih.gov/pubmed/28674449
http://dx.doi.org/10.1038/s41598-017-04558-z