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Targeted ‘knockdown’ of spliceosome function in mammalian cells
The existence of two sophisticated parallel splicing machineries in multicellular organisms has raised intriguing questions—ranging from their impact on proteome expansion to the evolution of splicing and of metazoan genomes. Exploring roles for the distinct splicing systems in vivo has, however, be...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549580/ https://www.ncbi.nlm.nih.gov/pubmed/15731334 http://dx.doi.org/10.1093/nar/gni041 |