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Targeted ‘knockdown’ of spliceosome function in mammalian cells

The existence of two sophisticated parallel splicing machineries in multicellular organisms has raised intriguing questions—ranging from their impact on proteome expansion to the evolution of splicing and of metazoan genomes. Exploring roles for the distinct splicing systems in vivo has, however, be...

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Detalles Bibliográficos
Autores principales: Matter, Nathalie, König, Harald
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549580/
https://www.ncbi.nlm.nih.gov/pubmed/15731334
http://dx.doi.org/10.1093/nar/gni041