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Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus

Nucleus pulposus (NP) cells reside in a physiologically hyperosmotic environment within the intervertebral disc. TonEBP/NFAT5 is an osmo-sensitive transcription factor that controls expression of genes critical for cell survival under hyperosmotic conditions. A recent report on NP and studies of oth...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Choi, Hyowon, Johnson, Zariel I., Tian, Jiwei, Shapiro, Irving M., Risbud, Makarand V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495809/
https://www.ncbi.nlm.nih.gov/pubmed/28674405
http://dx.doi.org/10.1038/s41598-017-04876-2