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The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design

Human parainfluenza viruses represent a leading cause of lower respiratory tract disease in children, with currently no available approved drug or vaccine. The viral surface glycoprotein haemagglutinin-neuraminidase (HN) represents an ideal antiviral target. Herein, we describe the first structure-b...

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Detalles Bibliográficos
Autores principales: Dirr, Larissa, El-Deeb, Ibrahim M., Chavas, Leonard M. G., Guillon, Patrice, Itzstein, Mark von
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495814/
https://www.ncbi.nlm.nih.gov/pubmed/28674426
http://dx.doi.org/10.1038/s41598-017-04656-y