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The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design
Human parainfluenza viruses represent a leading cause of lower respiratory tract disease in children, with currently no available approved drug or vaccine. The viral surface glycoprotein haemagglutinin-neuraminidase (HN) represents an ideal antiviral target. Herein, we describe the first structure-b...
Autores principales: | Dirr, Larissa, El-Deeb, Ibrahim M., Chavas, Leonard M. G., Guillon, Patrice, Itzstein, Mark von |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495814/ https://www.ncbi.nlm.nih.gov/pubmed/28674426 http://dx.doi.org/10.1038/s41598-017-04656-y |
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