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Opportunistic Pathogen Porphyromonas gingivalis Modulates Danger Signal ATP-Mediated Antibacterial NOX2 Pathways in Primary Epithelial Cells

Porphyromonas gingivalis, a major opportunistic pathogen in the etiology of chronic periodontitis, successfully survives in human gingival epithelial cells (GECs). P. gingivalis abrogates the effects of a host danger molecule, extracellular ATP (eATP)/P2X(7) signaling, such as the generation of reac...

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Detalles Bibliográficos
Autores principales: Roberts, JoAnn S., Atanasova, Kalina R., Lee, Jungnam, Diamond, Gill, Deguzman, Jeff, Hee Choi, Chul, Yilmaz, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495830/
https://www.ncbi.nlm.nih.gov/pubmed/28725637
http://dx.doi.org/10.3389/fcimb.2017.00291