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High expression of cyclin D1 is associated to high proliferation rate and increased risk of mortality in women with ER-positive but not in ER-negative breast cancers

PURPOSE: Cyclin D1 has a central role in cell cycle control and is an important component of estrogen regulation of cell cycle progression. We have previously shown that high cyclin D expression is related to aggressive features of ER-positive but not ER-negative breast cancer. The aims of the prese...

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Detalles Bibliográficos
Autores principales: Ahlin, Cecilia, Lundgren, Claudia, Embretsén-Varro, Elin, Jirström, Karin, Blomqvist, Carl, Fjällskog, M. -L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495873/
https://www.ncbi.nlm.nih.gov/pubmed/28528450
http://dx.doi.org/10.1007/s10549-017-4294-5