In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers

Zika virus (ZIKV) and the 4 dengue virus (DENV) serotypes are mosquito-borne Flaviviruses that are associated with severe neuronal and hemorrhagic syndromes. The mature flavivirus infectious virion has 90 envelope (E) protein homo-dimers that pack tightly to form a smooth protein coat with icosahedr...

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Detalles Bibliográficos
Autores principales: Metz, Stefan W., Gallichotte, Emily N., Brackbill, Alex, Premkumar, Lakshmanane, Miley, Michael J., Baric, Ralph, de Silva, Aravinda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495877/
https://www.ncbi.nlm.nih.gov/pubmed/28674411
http://dx.doi.org/10.1038/s41598-017-04767-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495877/
https://www.ncbi.nlm.nih.gov/pubmed/28674411
http://dx.doi.org/10.1038/s41598-017-04767-6

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