Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats

Hepatic mitochondrial function, APOC-III, and LPL are potential targets for triglyceride (TG)-lowering drugs. After 3 weeks of dietary treatment with the compound 2-(tridec-12-yn-1-ylthio)acetic acid (1-triple TTA), the hepatic mitochondrial FA oxidation increased more than 5-fold in male Wistar rat...

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Detalles Bibliográficos
Autores principales: Lindquist, Carine, Bjørndal, Bodil, Rossmann, Christine Renate, Tusubira, Deusdedit, Svardal, Asbjørn, Røsland, Gro Vatne, Tronstad, Karl Johan, Hallström, Seth, Berge, Rolf Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496034/
https://www.ncbi.nlm.nih.gov/pubmed/28473603
http://dx.doi.org/10.1194/jlr.M074849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496034/
https://www.ncbi.nlm.nih.gov/pubmed/28473603
http://dx.doi.org/10.1194/jlr.M074849

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