The Astrocytic S100B Protein with Its Receptor RAGE Is Aberrantly Expressed in SOD1(G93A) Models, and Its Inhibition Decreases the Expression of Proinflammatory Genes

Neuroinflammation is one of the major players in amyotrophic lateral sclerosis (ALS) pathogenesis, and astrocytes are significantly involved in this process. The astrocytic protein S100B can be released in pathological states activating the receptor for advanced glycation end products (RAGE). Differ...

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Detalles Bibliográficos
Autores principales: Serrano, Alessia, Donno, Claudia, Giannetti, Stefano, Perić, Mina, Andjus, Pavle, D'Ambrosi, Nadia, Michetti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496121/
https://www.ncbi.nlm.nih.gov/pubmed/28713206
http://dx.doi.org/10.1155/2017/1626204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496121/
https://www.ncbi.nlm.nih.gov/pubmed/28713206
http://dx.doi.org/10.1155/2017/1626204

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