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The Astrocytic S100B Protein with Its Receptor RAGE Is Aberrantly Expressed in SOD1(G93A) Models, and Its Inhibition Decreases the Expression of Proinflammatory Genes
Neuroinflammation is one of the major players in amyotrophic lateral sclerosis (ALS) pathogenesis, and astrocytes are significantly involved in this process. The astrocytic protein S100B can be released in pathological states activating the receptor for advanced glycation end products (RAGE). Differ...
Autores principales: | Serrano, Alessia, Donno, Claudia, Giannetti, Stefano, Perić, Mina, Andjus, Pavle, D'Ambrosi, Nadia, Michetti, Fabrizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496121/ https://www.ncbi.nlm.nih.gov/pubmed/28713206 http://dx.doi.org/10.1155/2017/1626204 |
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