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Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults

BACKGROUND: This study sought to evaluate gender and APOE genotype-related differences in the concentrations of cerebrospinal fluid (CSF) biomarkers for Alzheimer’s disease (AD) and cerebrovascular injury across the life span of cognitively normal adults. METHODS: CSF amyloid beta(1–42) (Aβ(42)), ph...

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Detalles Bibliográficos
Autores principales: Li, Ge, Shofer, Jane B., Petrie, Eric C., Yu, Chang-En, Wilkinson, Charles W., Figlewicz, Dianne P., Shutes-David, Andrew, Zhang, Jing, Montine, Thomas J., Raskind, Murray A., Quinn, Joseph F., Galasko, Douglas R., Peskind, Elaine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496132/
https://www.ncbi.nlm.nih.gov/pubmed/28673336
http://dx.doi.org/10.1186/s13195-017-0271-9