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Efficacy and safety evaluation of a novel trioxaquine in the management of cerebral malaria in a mouse model

BACKGROUND: The emergence of multidrug-resistant strains of Plasmodium falciparum poses a great threat of increased fatalities in cases of cerebral and other forms of severe malaria infections in which parenteral artesunate monotherapy is the current drug of choice. The study aimed to investigate in...

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Detalles Bibliográficos
Autores principales: Odhiambo, Onyango C., Wamakima, Hannah N., Magoma, Gabriel N., Kirira, Peter G., Malala, Bonface J., Kimani, Francis T., Muregi, Francis W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496145/
https://www.ncbi.nlm.nih.gov/pubmed/28673299
http://dx.doi.org/10.1186/s12936-017-1917-6