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Efficacy and safety evaluation of a novel trioxaquine in the management of cerebral malaria in a mouse model
BACKGROUND: The emergence of multidrug-resistant strains of Plasmodium falciparum poses a great threat of increased fatalities in cases of cerebral and other forms of severe malaria infections in which parenteral artesunate monotherapy is the current drug of choice. The study aimed to investigate in...
Autores principales: | Odhiambo, Onyango C., Wamakima, Hannah N., Magoma, Gabriel N., Kirira, Peter G., Malala, Bonface J., Kimani, Francis T., Muregi, Francis W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496145/ https://www.ncbi.nlm.nih.gov/pubmed/28673299 http://dx.doi.org/10.1186/s12936-017-1917-6 |
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