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A cross-sectional study to evaluate second line virological failure and elevated bilirubin as a surrogate for adherence to atazanavir/ritonavir in two urban HIV clinics in Lilongwe, Malawi

BACKGROUND: Malawi’s national antiretroviral therapy program provides atazanavir/ritonavir–based second line regimens which cause concentration-dependent rise in indirect bilirubin. We sought to determine if elevated bilirubin, as a surrogate of atazanavir/ritonavir adherence, can aid in the evaluat...

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Detalles Bibliográficos
Autores principales: Ongubo, Dennis Miyoge, Lim, Robertino, Tweya, Hannock, Stanley, Christopher Chikhosi, Tembo, Petros, Broadhurst, Richard, Gugsa, Salem, Ngongondo, McNeil, Speight, Colin, Heller, Tom, Phiri, Sam, Hosseinipour, Mina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496231/
https://www.ncbi.nlm.nih.gov/pubmed/28673254
http://dx.doi.org/10.1186/s12879-017-2528-0