JNK Pathway-Associated Phosphatase/DUSP22 Suppresses CD4(+) T-Cell Activation and Th1/Th17-Cell Differentiation and Negatively Correlates with Clinical Activity in Inflammatory Bowel Disease

This study aimed to investigate the role of JNK pathway-associated phosphatase (JKAP) in inflammatory bowel disease (IBD). JKAP expression was analyzed in the intestinal mucosa of 81 IBD patients and 25 healthy controls (HCs) by qPCR and immunoblotting. The correlations of JKAP with clinical activit...

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Detalles Bibliográficos
Autores principales: Zhou, Rui, Chang, Ying, Liu, Jing, Chen, Min, Wang, Hongling, Huang, Meifang, Liu, Shi, Wang, Xiaobing, Zhao, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496234/
https://www.ncbi.nlm.nih.gov/pubmed/28725226
http://dx.doi.org/10.3389/fimmu.2017.00781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496234/
https://www.ncbi.nlm.nih.gov/pubmed/28725226
http://dx.doi.org/10.3389/fimmu.2017.00781

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