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Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature

BACKGROUND: Systemic sclerosis (SSc; scleroderma) is an uncommon autoimmune rheumatic disease characterised by autoimmunity, vasculopathy and fibrosis. Gene expression profiling distinguishes scleroderma from normal skin, and can detect different subsets of disease, with potential to identify progno...

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Detalles Bibliográficos
Autores principales: Derrett-Smith, Emma C., Martyanov, Viktor, Chighizola, Cecilia B., Moinzadeh, Pia, Campochiaro, Corrado, Khan, Korsa, Wood, Tammara A., Meroni, Pier Luigi, Abraham, David J., Ong, Voon H., Lafyatis, Robert, Whitfield, Michael L., Denton, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496265/
https://www.ncbi.nlm.nih.gov/pubmed/28676069
http://dx.doi.org/10.1186/s13075-017-1360-7