Cargando…
Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature
BACKGROUND: Systemic sclerosis (SSc; scleroderma) is an uncommon autoimmune rheumatic disease characterised by autoimmunity, vasculopathy and fibrosis. Gene expression profiling distinguishes scleroderma from normal skin, and can detect different subsets of disease, with potential to identify progno...
Autores principales: | Derrett-Smith, Emma C., Martyanov, Viktor, Chighizola, Cecilia B., Moinzadeh, Pia, Campochiaro, Corrado, Khan, Korsa, Wood, Tammara A., Meroni, Pier Luigi, Abraham, David J., Ong, Voon H., Lafyatis, Robert, Whitfield, Michael L., Denton, Christopher P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496265/ https://www.ncbi.nlm.nih.gov/pubmed/28676069 http://dx.doi.org/10.1186/s13075-017-1360-7 |
Ejemplares similares
-
Association of anti-RNA polymerase III autoantibodies and cancer in scleroderma
por: Moinzadeh, Pia, et al.
Publicado: (2014) -
Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies
por: Pendergrass, Sarah A., et al.
Publicado: (2012) -
A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis
por: Taroni, Jaclyn N., et al.
Publicado: (2017) -
Outcomes linked to eligibility for stem cell transplantation trials in diffuse cutaneous systemic sclerosis
por: Spierings, Julia, et al.
Publicado: (2021) -
Gene expression changes reflect clinical response in a placebo-controlled randomized trial of abatacept in patients with diffuse cutaneous systemic sclerosis
por: Chakravarty, Eliza F., et al.
Publicado: (2015)