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Drosophila CP190- and dCTCF-mediated enhancer blocking is augmented by SUMOylation
BACKGROUND: Chromatin insulators shield promoters and chromatin domains from neighboring enhancers or chromatin regions with opposing activities. Insulator-binding proteins and their cofactors mediate the boundary function. In general, covalent modification of proteins by the small ubiquitin-like mo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496309/ https://www.ncbi.nlm.nih.gov/pubmed/28680483 http://dx.doi.org/10.1186/s13072-017-0140-6 |