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Drosophila CP190- and dCTCF-mediated enhancer blocking is augmented by SUMOylation

BACKGROUND: Chromatin insulators shield promoters and chromatin domains from neighboring enhancers or chromatin regions with opposing activities. Insulator-binding proteins and their cofactors mediate the boundary function. In general, covalent modification of proteins by the small ubiquitin-like mo...

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Detalles Bibliográficos
Autores principales:	Jox, Theresa, Buxa, Melanie K., Bohla, Dorte, Ullah, Ikram, Mačinković, Igor, Brehm, Alexander, Bartkuhn, Marek, Renkawitz, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496309/ https://www.ncbi.nlm.nih.gov/pubmed/28680483 http://dx.doi.org/10.1186/s13072-017-0140-6

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