Cargando…

Sustained hyperosmolarity increses TGF-ß1 and Egr-1 expression in the rat renal medulla

BACKGROUND: Although TGF-ß and the transcription factor Egr-1 play an important role in both kidney fibrosis and in response to acute changes of renal medullary osmolarity, their role under sustained hypo- or hyperosmolar conditions has not been elucidated. We investigated the effects of chronic hyp...

Descripción completa

Detalles Bibliográficos
Autores principales: Mózes, Miklós M., Szoleczky, Petra, Rosivall, László, Kökény, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496335/
https://www.ncbi.nlm.nih.gov/pubmed/28673338
http://dx.doi.org/10.1186/s12882-017-0626-2