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Sustained hyperosmolarity increses TGF-ß1 and Egr-1 expression in the rat renal medulla
BACKGROUND: Although TGF-ß and the transcription factor Egr-1 play an important role in both kidney fibrosis and in response to acute changes of renal medullary osmolarity, their role under sustained hypo- or hyperosmolar conditions has not been elucidated. We investigated the effects of chronic hyp...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496335/ https://www.ncbi.nlm.nih.gov/pubmed/28673338 http://dx.doi.org/10.1186/s12882-017-0626-2 |