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Sustained hyperosmolarity increses TGF-ß1 and Egr-1 expression in the rat renal medulla

BACKGROUND: Although TGF-ß and the transcription factor Egr-1 play an important role in both kidney fibrosis and in response to acute changes of renal medullary osmolarity, their role under sustained hypo- or hyperosmolar conditions has not been elucidated. We investigated the effects of chronic hyp...

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Detalles Bibliográficos
Autores principales:	Mózes, Miklós M., Szoleczky, Petra, Rosivall, László, Kökény, Gábor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496335/ https://www.ncbi.nlm.nih.gov/pubmed/28673338 http://dx.doi.org/10.1186/s12882-017-0626-2

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