Potent long-acting rhFGF21 analog for treatment of diabetic nephropathy in db/db and DIO mice

BACKGROUND: Fibroblast growth factor 21 (FGF21) is an endocrine-acting hormone that has the potential to treat diabetic nephropathy. However, development of FGF21 into a therapeutic has been hindered due to its low intrinsic bio-stability. In our previous study, we have developed a recombinant human...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Longwei, Wang, Huiyan, Xie, Junjun, Chen, Zilu, Li, Xiaokun, Niu, Jianlou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496364/
https://www.ncbi.nlm.nih.gov/pubmed/28676059
http://dx.doi.org/10.1186/s12896-017-0368-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496364/
https://www.ncbi.nlm.nih.gov/pubmed/28676059
http://dx.doi.org/10.1186/s12896-017-0368-z

Ejemplares similares