MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer

The two murine double minute (MDM) family members MDM2 and MDMX are at the center of an intense clinical assessment as molecular target for the management of cancer. Indeed, the two proteins act as regulators of P53, a well-known key controller of the cell cycle regulation and cell proliferation tha...

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Detalles Bibliográficos
Autores principales: Tisato, Veronica, Voltan, Rebecca, Gonelli, Arianna, Secchiero, Paola, Zauli, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496368/
https://www.ncbi.nlm.nih.gov/pubmed/28673313
http://dx.doi.org/10.1186/s13045-017-0500-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496368/
https://www.ncbi.nlm.nih.gov/pubmed/28673313
http://dx.doi.org/10.1186/s13045-017-0500-5

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