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Therapeutic effect of a novel histone deacetylase 6 inhibitor, CKD-L, on collagen-induced arthritis in vivo and regulatory T cells in rheumatoid arthritis in vitro

BACKGROUND: Histone deacetylase (HDAC) inhibitor has recently been reported to have a therapeutic effect as an anti-inflammatory agent in collagen-induced arthritis (CIA). We investigated the therapeutic effect of a new selective HDAC6 inhibitor, CKD-L, compared to ITF 2357 or Tubastatin A on CIA an...

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Detalles Bibliográficos
Autores principales: Oh, Bo Ram, Suh, Dong-hyeon, Bae, Daekwon, Ha, Nina, Choi, Young Il, Yoo, Hyun Jung, Park, Jin Kyun, Lee, Eun Young, Lee, Eun Bong, Song, Yeong Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496370/
https://www.ncbi.nlm.nih.gov/pubmed/28673326
http://dx.doi.org/10.1186/s13075-017-1357-2