Pharmacokinetic and pharmacodynamic modeling of oral mitiglinide on glucose lowering in healthy Chinese volunteers

BACKGROUND: Mitiglinide is a widely used agent for diabetic treatment. We established a pharmacokinetic-pharmacodynamic (PK-PD) model to illustrate the relationship between mitiglinide plasma concentration and its glucose lowering effects in healthy volunteers. METHODS: The volunteers participated i...

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Detalles Bibliográficos
Autores principales: Liu, Shijia, Chen, Peidong, Zhao, Yang, Dai, Guoliang, Sun, Bingting, Wang, Yao, Ding, Anwei, Ju, Wenzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496406/
https://www.ncbi.nlm.nih.gov/pubmed/28676080
http://dx.doi.org/10.1186/s40360-017-0161-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496406/
https://www.ncbi.nlm.nih.gov/pubmed/28676080
http://dx.doi.org/10.1186/s40360-017-0161-6

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