Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes

Decades ago, it was proposed that Na transport in cardiac myocytes is modulated by large changes in cytoplasmic Na concentration within restricted subsarcolemmal spaces. Here, we probe this hypothesis for Na/K pumps by generating constitutive transsarcolemmal Na flux with the Na channel opener verat...

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Detalles Bibliográficos
Autores principales: Lu, Fang-Min, Hilgemann, Donald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496509/
https://www.ncbi.nlm.nih.gov/pubmed/28606910
http://dx.doi.org/10.1085/jgp.201711780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496509/
https://www.ncbi.nlm.nih.gov/pubmed/28606910
http://dx.doi.org/10.1085/jgp.201711780

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