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Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin

Soluble cytosolic proteins vital to axonal and presynaptic function are synthesized in the neuronal soma and conveyed via slow axonal transport. Our previous studies suggest that the overall slow transport of synapsin is mediated by dynamic assembly/disassembly of cargo complexes followed by short-r...

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Detalles Bibliográficos
Autores principales: Ganguly, Archan, Han, Xuemei, Das, Utpal, Wang, Lina, Loi, Jonathan, Sun, Jichao, Gitler, Daniel, Caillol, Ghislaine, Leterrier, Christophe, Yates, John R., Roy, Subhojit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496608/
https://www.ncbi.nlm.nih.gov/pubmed/28559423
http://dx.doi.org/10.1083/jcb.201604028