Rab2 promotes autophagic and endocytic lysosomal degradation

Rab7 promotes fusion of autophagosomes and late endosomes with lysosomes in yeast and metazoan cells, acting together with its effector, the tethering complex HOPS. Here we show that another small GTPase, Rab2, is also required for autophagosome and endosome maturation and proper lysosome function i...

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Detalles Bibliográficos
Autores principales: Lőrincz, Péter, Tóth, Sarolta, Benkő, Péter, Lakatos, Zsolt, Boda, Attila, Glatz, Gábor, Zobel, Martina, Bisi, Sara, Hegedűs, Krisztina, Takáts, Szabolcs, Scita, Giorgio, Juhász, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496615/
https://www.ncbi.nlm.nih.gov/pubmed/28483915
http://dx.doi.org/10.1083/jcb.201611027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496615/
https://www.ncbi.nlm.nih.gov/pubmed/28483915
http://dx.doi.org/10.1083/jcb.201611027

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