mTOR controls ChREBP transcriptional activity and pancreatic β cell survival under diabetic stress

Impaired nutrient sensing and dysregulated glucose homeostasis are common in diabetes. However, how nutrient-sensitive signaling components control glucose homeostasis and β cell survival under diabetic stress is not well understood. Here, we show that mice lacking the core nutrient-sensitive signal...

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Detalles Bibliográficos
Autores principales: Chau, Gia Cac, Im, Dong Uk, Kang, Tong Mook, Bae, Jeong Mo, Kim, Won, Pyo, Suhkneung, Moon, Eun-Yi, Um, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496625/
https://www.ncbi.nlm.nih.gov/pubmed/28606928
http://dx.doi.org/10.1083/jcb.201701085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496625/
https://www.ncbi.nlm.nih.gov/pubmed/28606928
http://dx.doi.org/10.1083/jcb.201701085

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