Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa

Exophilin-8 has been reported to play a role in anchoring secretory granules within the actin cortex, due to its direct binding activities to Rab27 on the granule membrane and to F-actin and its motor protein, myosin-Va. Here, we show that exophilin-8 accumulates granules in the cortical F-actin net...

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Detalles Bibliográficos
Autores principales: Fan, Fushun, Matsunaga, Kohichi, Wang, Hao, Ishizaki, Ray, Kobayashi, Eri, Kiyonari, Hiroshi, Mukumoto, Yoshiko, Okunishi, Katsuhide, Izumi, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496739/
https://www.ncbi.nlm.nih.gov/pubmed/28673385
http://dx.doi.org/10.7554/eLife.26174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496739/
https://www.ncbi.nlm.nih.gov/pubmed/28673385
http://dx.doi.org/10.7554/eLife.26174

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