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Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood
High temperature requirement factor A3 (HtrA3), a member of the HtrA protease family, is highly expressed in the developing placenta, including the maternal decidual cells in both mice and humans. In this study we deleted the HtrA3 gene in the mouse and crossed females carrying zero, one, or two Htr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496872/ https://www.ncbi.nlm.nih.gov/pubmed/28676687 http://dx.doi.org/10.1038/s41598-017-04867-3 |