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3D models of the hematopoietic stem cell niche under steady-state and active conditions

Hematopoietic stem cells (HSCs) in the bone marrow are able to differentiate into all types of blood cells and supply the organism each day with billions of fresh cells. They are applied to cure hematological diseases such as leukemia. The clinical need for HSCs is high and there is a demand for bei...

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Detalles Bibliográficos
Autores principales: Rödling, Lisa, Schwedhelm, Ivo, Kraus, Saskia, Bieback, Karen, Hansmann, Jan, Lee-Thedieck, Cornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496931/
https://www.ncbi.nlm.nih.gov/pubmed/28676663
http://dx.doi.org/10.1038/s41598-017-04808-0