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CRISPR-Cas9 targeted disruption of the yellow ortholog in the housefly identifies the brown body locus
The classic brown body (bwb) mutation in the housefly Musca domestica impairs normal melanization of the adult cuticle. In Drosophila melanogaster, a reminiscent pigmentation defect results from mutations in the yellow gene encoding dopachrome conversion enzyme (DCE). Here, we demonstrate that the b...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496933/ https://www.ncbi.nlm.nih.gov/pubmed/28676649 http://dx.doi.org/10.1038/s41598-017-04686-6 |