CRISPR-Cas9 targeted disruption of the yellow ortholog in the housefly identifies the brown body locus

The classic brown body (bwb) mutation in the housefly Musca domestica impairs normal melanization of the adult cuticle. In Drosophila melanogaster, a reminiscent pigmentation defect results from mutations in the yellow gene encoding dopachrome conversion enzyme (DCE). Here, we demonstrate that the b...

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Detalles Bibliográficos
Autores principales: Heinze, Svenia D., Kohlbrenner, Tea, Ippolito, Domenica, Meccariello, Angela, Burger, Alexa, Mosimann, Christian, Saccone, Giuseppe, Bopp, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496933/
https://www.ncbi.nlm.nih.gov/pubmed/28676649
http://dx.doi.org/10.1038/s41598-017-04686-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496933/
https://www.ncbi.nlm.nih.gov/pubmed/28676649
http://dx.doi.org/10.1038/s41598-017-04686-6

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